Sorbinil (standaard)

Sorbinil (Standard) is the analytical standard of Sorbinil. This product is intended for research and analytical applications. Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway[1][2].

68367-52-2

12352100

Aldose Reductase; Reference Standards

Metabolic Enzyme/Protease; Others

Metabolic Disease

O=C([C@@]12C3=CC(F)=CC=C3OCC1)NC(N2)=O

C11H9FN2O3

236.20

[1]Huang Q, et al. Sorbinil, an Aldose Reductase Inhibitor, in Fighting Against Diabetic Complications. Med Chem. 2019;15 (1) :3-7.|[2]Chang KC, et al. Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. Chem Biol Interact. 2013 Feb 25;202 (1-3) :283-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-50289R/

Reference Standards