SORD Antilichaam

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.

6652

Q00796

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human SORD (NP_003095.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

Mouse testis

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 38kDa

IgG

WB: 1:500 - 1:2000

SORD

Mouse kidney

Mouse liver

Rat liver

Sorbitol dehydrogenase

Homo sapiens

SORD, SORD1, sorbitol dehydrogenase, HEL-S-95n

WB

Liquid