SOX12 Antilichaam - C-terminaal gebied: Biotine (ARP3330_P050-Biotine)

SRY (sex determining region Y) -box 12

SOX22

6666

O15370

NP_008874

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the C terminal region of human SOX12

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY) . Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The SOX12 gene encodes a protein that was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

SRM; POLD2; SMAD4

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 92%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Weiss, M.A. et al., (2001) Mol. Endocrinol. 15 (3), 353-362

Wet Ice

315

SOX12

SOX12

Rabbit

Transcription factor SOX-12

NM_006943

DCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY