SOX17 Antilichaam

SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2) . SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types (3,4) . SOX17 is also essential for acquisition and maintenance of arterial identity (5) .

64321

Q9H6I2

NP_071899

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

SOX17 antibody is affinity chromatography purified via peptide column.

Cat. No. 1211 - HepG2 Cell Lysate

1 mg/mL

SOX17 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SOX17 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

SOX17 antibody is human, mouse and rat reactive. SOX17 is predicted to not cross-react with other SOX proteins.

SOX17

RY (sex determining region Y) -box 17

Homo sapiens

Kanai Y, Kanai-Azuma M, Noce T, et al. Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis. J. Cell Biol. 1996; 133:667-81.

Jiang T, Hou CC, She ZY, et al. The SOX gene family: function and regulation in testis determination and male fertility maintenance. Mol. Biol. Rep. 2013; 40:2187-94.

Francois M, Koopman P, and Beltrame M. SoxF genes: key players in the development of the cardiovascular system. Int. J. Biochem. Cell Biol. 2010; 42:445-8.

Kim I, Saunders TL, and Morrison SJ. Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 2007; 130:470-83.

SOX17 Antibody: VUR3, Transcription factor SOX-17

ELISA, WB, IF

11967991

Liquid