SP110 Antilichaam - C-terminaal gebied: Biotine (ARP36125_P050-Biotine)

SP110 nuclear body protein

IPR1, VODI, IFI41, IFI75

3431

Q9HB58

NP_536349

Human, Dog, Pig

The immunogen is a synthetic peptide directed towards the C terminal region of human SP110

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

UBC; CEBPA; OSGEP; TSC22D1; TTR; TK1; SMN1; CDKN1A; ANXA7; ZSCAN9; NAP1L2; RUNX3; NDUFV2

Biotin

Polyclonal Antibody

WB

Affinity Purified

SP110 is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Dog: 79%; Human: 100%; Pig: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

81kDa

Cliffe, S.T., (2007) Prenat. Diagn. 27 (7), 674-676

Wet Ice

713

SP110

SP110

Rabbit

Sp110 nuclear body protein

NM_080424

LITEMYTVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVL