SP141
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1253491-42-7
C07383-5mg
MDM2/MDMX
Apoptosis
COC1=CC2=C (C=C1) NC3=C2C=CN=C3C4=CC=CC5=CC=CC=C54
C22H16N2O
SP141 is a new class of MDM2 inhibitor that promotes MDM2 auto-ubiquitination and degradation, and reduces levels of MDM2 in pancreatic cancer cell lines, as well as their proliferation and ability to form tumors in nude mice. SP141 inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM (0.38–0.50 μM) in a p53-independent manner.
3 years -20°C powder
Beschrijving
SP141 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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