SPA-10091-HCl
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
C04931-1mg
DOT1
Epigenetics
SPA-10091-HCl is a degrader of DOT1L that selectively degrades DOT1L protein through the nuclear ubiquitin-proteasome pathway, thereby suppressing H3K79 methylation in CRPC cells. It also inhibits DOT1L enzymatic activity with an IC50 of 0.87 μM, induces apoptosis, and significantly reduces tumor growth in vivo.
Beschrijving
SPA-10091-HCl Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
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Each
MS pipette, variable vol µme 10~100 µL
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MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
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MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS pipette, variable vol µme 1000~10000 µL
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