SPARC Antilichaam

Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.

6678

P09486

NP_003109.1

Human

SPARC antibody was raised against a peptide sequence around aa.52~56 (V-G-E-F-D) derived from Human SPARC.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

42 kDa

This antibody detects endogenous level of total SPARC protein.

Western Blot: 1:500~1:1000

SPARC

Secreted protein, acidic, cysteine-rich (osteonectin)

Homo sapiens

Kelm R. J. Jr., Mann K. G. Blood 75:1105-1113 (1990) Wewer U. M., Albrechtsen R., Fisher L. W., Young M. F., Termine J. D. Am. J. Pathol. 132:345-355 (1988) Kuhn C., Mason R. J. Am. J. Pathol. 147:1759-1769 (1995)

ON, ABL, JTK7, ON, BM-40

WB

4507171

Liquid