SPART Antilichaam - middengebied: Biotine (ARP55162_P050-Biotine)

Spartin

SPG20, TAHCCP1

23111

Q8N0X7

NP_055902

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SPG20

This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) .

UBC; WWOX; ITCH; PLIN3; SMURF2; ZFYVE9; APP; EPS15; SMURF1; WWP2; WWP1; SUMO2; KLC2; AIFM1; VIM; NCL; LMNB1; KPNB1; KIF5B; HSPD1; HSPA9; HSPA5; HADHA; ACSL4; ACSL3; DYNC1H1; COPA; CLTC; TUBA1A

Biotin

Polyclonal Antibody

WB

Affinity Purified

SPG20 is supported by BioGPS gene expression data to be expressed in OVCAR3

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

73kDa

Wet Ice

666

SPART

SPART

Rabbit

Spartin

NM_015087

ASWVSWGLVKGAEITGKAIQKGASKLRERIQPEEKPVEVSPAVTKGLYIA