SPATA19 Antilichaam

SPATA19 Antibody: SPATA19, also known as SPERGEN1, was initially identified as a testis-specific protein that localizes to the surface of mitochondria in the middle piece of mature spermatozoa. Recent experiments have shown that elevated levels of SPATA19 have been found in basal cell carcinomas and prostate cancers, suggesting that SPATA19 may serve as a putative cancer biomarker and a target for cancer immunotherapy.

219938

Q7Z5L4

EAW67810

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

SPATA19 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (82%)

SPATA19 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SPATA19 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgY

At least two isoforms of SPATA19 are known to exist; this antibody will detect both isoforms. SPATA19 antibody is predicted to not cross-react with other SPATA family members.

SPATA19

Spermatogenesis associated 19

Homo sapiens

Miyamoto T, Sengoku K, Hasuike S, et al. Isolation and expression analysis of the human testis-specific gene, SPERGEN-1, a spermatogenic cell-specific gene-1. J. Assist. Reprod. Genet. 2003; 20:101-4.

Doiguchi M, Mori T, Toshimori K, et al. Spergen-1 might be an adhesive molecule associated with mitochondria in the middle piece of spermatozoa. Dev. Biol. 2002; 252:127-37.

Ghafouri-Fard S, Abbasi A, Moslehi H, et al. Elevated levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features. Br. J. Dermatol. 2010; 162:772-9

Ghafouri-Fard S, Ousati Ashtiani Z, Sabah Golian B, et al. Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer. Arch. Med. Res. 2010; 41:195-200.

SPATA19 Antibody: CT132, SPAS1, spergen1, SPERGEN1, Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1

ELISA, WB

28376652

Liquid