Spautin-1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.
Unconjugated
Tan solid
-20°C
Beschrijving
Spautin-1 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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