SPDEF Antilichaam

The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

25803

O95238

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human SPDEF (NP_036523.1) .

Unconjugated

Primary Antibodies

Cancer, Transcription

Affinity purification

Rat ovary

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 50kDa

IgG

SPDEF

SAM pointed domain containing ETS transcription factor

Homo sapiens

SPDEF, PDEF, RP11-375E1__A.3, bA375E1.3

WB, IHC, IF

Liquid