SPDYA Antibody - middle area : HRP (ARP55846 P050-HRP)

Speedy homolog A (Xenopus laevis)

SPY1, SPDY1, RINGO3, RINGOA

245711

Q5MJ70

NP_877433

Human

The immunogen is a synthetic peptide directed towards the middle region of human SPDYA

SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

CDK2; UBC; SKP2; CDKN1B

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

36kDa

McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945

Wet Ice

313

SPDYA

SPDYA

Rabbit

Speedy protein A

NM_182756

HTAGVTEKHSQDSYNSLSMDIIGDPSQAYTGSEVVNDHQSNKGKKTNFLK