SPDYA Antilichaam

SPDYA (speedy homolog A (Drosophila) ) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

245711

Q5MJ70

Q5MJ70

Human

This SPDYA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SPDYA.

Unconjugated

Primary Antibodies

Cell Cycle

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

36 kDa

Rabbit Ig

SPDYA

Speedy protein A

Homo sapiens

Ke, Q., et al. Exp. Mol. Pathol. 87 (3) :167-172 (2009)

Dinarina, A., et al. FEBS Lett. 583 (17) :2772-2778 (2009)

McAndrew, C.W., et al. Cell Cycle 8 (1) :66-75 (2009)

HGNC:30613

WB, IHC-P, Flow

94730574

Liquid