SPI-05
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM) . SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression[1].
5463-64-9
NSC 5067
12352005
H315, H319
E1/E2/E3 Enzyme
Metabolic Enzyme/Protease
Cancer-programmed cell death
Cancer
NC1=CC=C(C2=C1C=CC=C2)/N=N/C(C=C3)=CC([S](=O)(O)=O)=C3/C=C/C(C=CC(/N=N/C(C4=C5C=CC=C4)=CC=C5N)=C6)=C6[S](=O)(O)=O
C34H26N6O6S2
678.74
H315, H319
[1]Madu IG, et al. Identification and characterization of a new chemotype of noncovalent SENP inhibitors. ACS Chem Biol. 2013 Jul 19;8 (7) :1435-41.
Room Temperature
4°C (Powder, sealed storage, away from moisture and light)
http://file.medchemexpress.com/batch_PDF/HY-W342380/SPI-05-SDS-MedChemExpress.pdf
Reference compound2
No Development Reported
Beschrijving
SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM) . SPI-05 is promising for research of cancers, such as prostate
Specificaties
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