SPIC Antilichaam - middelste regio : HRP (ARP39882_P050-HRP)

Spi-C transcription factor (Spi-1/PU.1 related)

SPI-C

121599

Q8N5J4

NP_689536

Human, Cow, Horse, Pig

The immunogen is a synthetic peptide directed towards the middle region of human SPIC

SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. SPIC is a transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC regulates VCAM1 gene expression.

APP

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Horse: 79%; Human: 100%; Pig: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

29kDa

Carlsson, R., (2006) Biochem. Biophys. Res. Commun. 344 (4), 1155-1160

Wet Ice

248

SPIC

SPIC

Rabbit

Transcription factor Spi-C

NM_152323

LQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHD