SPR Antilichaam

SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4) . Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

6697

P35270

P35270

Human, Mouse

This SPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human SPR.

Unconjugated

Primary Antibodies

Obesity, Neuroscience, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

28 kDa

Rabbit Ig

For WB starting dilution is: 1:1000

SPR

Sepiapterin reductase

Homo sapiens

Leu-Semenescu, S., et al. Sleep 33 (3) :307-314 (2010) Schnetz-Boutaud, N.C., et al. Genes Brain Behav. 8 (8) :753-757 (2009) Clot, F., et al. Brain 132 (PT 7), 1753-1763 (2009)

Sepiapterin reductase, SPR, SPR

WB

464801

Liquid