Spuit A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae. Syringolin A exhibits anti-proliferative activity against a variety of cancer cells (IC50 for SK-N-SH, LAN-1, SKOV3 is 20-25 µM), induces apoptosis in SK-N-SH through upregulation of p53 expression and downregulation of Akt/PKB proteins[1].
212115-96-3
12352211
Akt; Apoptosis; MDM-2/p53
Apoptosis; PI3K/Akt/mTOR
Cancer
CC(C)[C@@H](C(O)=O)NC(N[C@H](C(N[C@@H]1C(N[C@@H](C(C)C)/C=C/C(NCC/C=C/1)=O)=O)=O)C(C)C)=O
C24H39N5O6
493.60
[1]Coleman CS, et al., Syringolin A, a new plant elicitor from the phytopathogenic bacterium Pseudomonas syringae pv. syringae, inhibits the proliferation of neuroblastoma and ovarian cancer cells and induces apoptosis. Cell Prolif. 2006 Dec;39 (6) :599-609.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N15314/
Natural Products
No Development Reported
Beschrijving
Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae. Syringolin A exhibits anti-proliferative activity
Specificaties
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