SR-717
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 µM) . It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC’s.
Unconjugated
Off-white solid
-20°C
Beschrijving
SR-717 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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