SR-717 lithium
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2375421-09-1
C07358-5mg
STING
Immunology & Inflammation
[Li]OC (=O) C1=C (NC (=O) C2=NN=C (C=C2) [N]3C=CN=C3) C=C (F) C (=C1) F
C15H8F2LiN5O3
SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.
3 years -20°C powder
Beschrijving
SR-717 lithium Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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