SREBP-1 (fosfo Ser439) Antilichaam

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway By similarity. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') . Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') .

6720

P36956

NP_001005291.1

Human, Rat

SREBP-1 (phospho Ser439) antibody was raised against a peptide sequence around phosphorylation site of serine439 (Q-S-S (p) -P-L) derived from Human SREBP-1 .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

122 kDa

IgG

The antibody detects endogenous level of SREBP-1 only when phosphorylated at serine 439.

Western Blot: 1:500~1:1000

SREBF1

Sterol regulatory element binding transcription factor 1

Homo sapiens

Bengoechea-Alonso MT, Ericsson J (2006) Cell Cycle 5, 1708-18

SRBP1, SREBF1, SREBP1, sterol regulatory element-binding protein 1

WB

52630419

Liquid