SRP72 Antilichaam

This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER) . The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

6731

O76094

Human

A synthetic peptide of human SRP72

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, pH7.3.

None

Blue Ice

Store at 4˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

SRP72

Jurkat

LO2

U-87MG

Signal recognition particle subunit SRP72

Homo sapiens

Signal recognition particle subunit SRP72, SRP72, Signal recognition particle 72 kDa protein, SRP72

WB, IHC, IF, Flow

Liquid