SRSF10 Antilichaam - C-terminalgebied: HRP (ARP41083_P050-HRP)

Serine and arginine rich splicing factor 10

NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149

10772

O75494

NP_473357

Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1

This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.

STAU1; WWOX; SUZ12; EED; RNF2; EZH2; HECW2; TRA2B; SRSF4; SRSF1; CSNK2A1; EIF4A3; MAGOH; PAXIP1; BARD1; SAP18; VTN; TCOF1; SRSF6; S100A9; PRKDC; NHP2L1; NFIA; SEPT2; MSH2; IK; EPRS; DHX15; BCAS2; TRIM55; THOC6; ZNF687; SMU1; TRMT112; TRA2A; PHGDH; NCSTN

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Shi, Y. (2007) Mol. Cell 28 (1), 79-90

Wet Ice

262

SRSF10

SRSF10

Rabbit

Serine/arginine-rich splicing factor 10

NM_054016

KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK