
SRT1720 HCl
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SIRT1 activator (EC1.5 = 0.16 µM, max activation = 781%) .1 It reduced glucose levels and hyperinsulinemia in DIO, Lepob/ob mice and Zucker fa/fa rats. SRT1720 enhanced endurance running and protected against diet-induced obesity and insulin resistance via enhancement of oxidative metabolism in skeletal muscle, liver, and brown adipose tissue.2 It induced mitochondrial biogenesis in oxidant-induced renal proximal tube cell injury.3 SRT1720 repressed circadian clock gene expression and decreased H3 K9/K14 acetylation in a time-specific manner.4 It attenuated angiotensin II-induced atherosclerosis by inhibiting the vascular inflammatory response.5
Unconjugated
White solid
-20°C
Beschrijving
SRT1720 HCl Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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