SSB-antilichaam

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly (U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

6741

P05455

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1) .

Unconjugated

Primary Antibodies

Immunology

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 47kDa

IgG

SSB

LO2

HepG2

293T

Sjogren syndrome antigen B (autoantigen La)

Homo sapiens

SSB, LARP3, La, La/SSB

WB, IHC, IF

Liquid