SSX2 Mouse Monoclonal Antibody [Kloon ID: LBI4D10]

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Carrier-free (BSA/glycerol-free) SSX2 mouse monoclonal antibody, clone LBI4D10

CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX

Homo sapiens SSX family member 2 (SSX2), transcript variant 1, mRNA.

6757

Q16385

Unconjugated

WB 1:2000, IHC 1:50, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SSX2

https://www.ncbi.nlm.nih.gov/gene/?term=6757

https://www.uniprot.org/uniprot/Q16385