ST-034307
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 μM . Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC11. It was also shown to inhibit AC1 stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells. It enhanced μ-opioid receptor-mediated inhibition of AC1 but it blocked heterologous sensitization of AC1 caused by chronic μ-opioid receptor activation.1 Displays analgesic properties in a mouse model of inflammatory pain.1
Unconjugated
Yellow solid
RT
Beschrijving
ST-034307 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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