ST-CY14
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NR4A, Mitochondrial Metabolism
Endocrinology/Hormones, Metabolism
ST-CY14 is an inhibitor of the Nur77-PPARγ interaction with an EC50 of 3.15 μM. It binds to Nur77 (Kd=32 nM) to prevent its ubiquitination and degradation by PPARγ, reducing fatty acid uptake and mitochondrial respiration, and inhibiting the transcription of CD36 and FABP4. ST-CY14 suppresses proliferation and migration of MCF7 and MDA-MB-231 cancer cells and impedes tumor growth and bone metastasis in mouse models.
C139H237N57O31S2
3266.86
Ice Packs
-20°C
Beschrijving
ST-CY14 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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