ST14 Antilichaam

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

6768

Q9Y5Y6

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 100kDa

IgG

ST14

Mouse liver

Suppression of tumorigenicity 14 (colon carcinoma)

Homo sapiens

ST14, HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14

WB, IHC, IF

Liquid