STAB2 Antilichaam

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF) -like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

55576

Q8WWQ8

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_060034.9) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction, Stem Cell

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 277kDa

IgG

WB: 1:500 - 1:2000

STAB2

BT-474

Mouse liver

Mouse eye

Mouse kidney

Rat liver

Stabilin 2

Homo sapiens

FEEL2, FELE-2, FELL2, FEX2, HARE, SCARH1, stabilin-2, CD44-like precursor FELL, FAS1 EGF-like and X-link domain containing adhesion molecule-2, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2, hepatic hyaluronan clearance receptor, hyaluronan receptor for endocytosis, hyaluronic acid receptor for endocytosis

WB

Liquid