STARD4 Antilichaam

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) .

134429

Q96DR4

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 24kDa

IgG

WB: 1:500 - 1:2000

STARD4

Rat liver

StAR related lipid transfer domain containing 4

Homo sapiens

StAR-related lipid transfer protein 4, START domain containing 4, sterol regulated, START domain-containing protein 4, StAR-related lipid transfer (START) domain containing 4

WB

Liquid