STAT1 Antilichaam

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

6772

P42224

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT1 (NP_009330.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription, Inflammasomes

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 91kDa

IgG

STAT1

Signal transducer and activator of transcription 1, 91kDa

Homo sapiens

STAT1 alpha Antibody: CANDF7, ISGF-3, STAT91

WB, IHC, IF, IP

Liquid