STAT1 Antilichaam - N-terminalgebied: FITC (ARP33373_P050-FITC)

Signal transducer and activator of transcription 1, 91kDa

CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91

6772

P42224

NP_009330

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1

STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

HUWE1; ISG15; PIAS1; UBC; STAT1; EIF1AD; OTUD4; LMO2; GNB2; DTX3L; EGFR; NAA15; SNX6; CAND1; VPS29; GSPT2; JMJD6; RTF1; HSPA4L; ATG7; YAP1; PAWR; KARS; IDE; CTTN; VPS26A; HIRIP3; NAA10; TSNAX; TBCD; SNX2; SNX1; SHMT2; SHMT1; SARS; ATP6V1C1; APEH; USP13; E

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Dog: 84%; Guinea Pig: 92%; Horse: 84%; Human: 100%; Mouse: 90%; Pig: 84%; Rabbit: 92%; Rat: 84%; Sheep: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

87kDa

Battle, T.E., (2006) Cancer Res. 66 (7), 3649-3657

Wet Ice

750

STAT1

STAT1

Rabbit

Signal transducer and activator of transcription 1-alpha/beta

NM_007315

MCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMY