STAT1 Mouse Monoclonal Antibody [Kloon ID: LBI15H3]

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Carrier-free (BSA/glycerol-free) STAT1 mouse monoclonal antibody, clone LBI15H3

CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Homo sapiens signal transducer and activator of transcription 1 (STAT1), transcript variant beta, mRNA.

6772

P42224

Unconjugated

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

WB 1:2000 IHC 1:50 IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

STAT1

https://www.ncbi.nlm.nih.gov/gene/?term=6772

https://www.uniprot.org/uniprot/P42224