STAT3 (fosfo Ser727) Antilichaam

Transcription factor that binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

6774

P40763

NP_003141.2

Human, Mouse, Rat

STAT3 (Phospho-Ser727) antibody was raised against a peptide sequence around phosphorylation site of serine 727 (P-M-S (p) -P-R) derived from Human STAT3.

Unconjugated

Primary Antibodies

Phospho-Specific, Apoptosis, Cancer

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

88 kDa

This antibody detects endogenous level of STAT3 only when phosphorylated at serine 727.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

STAT3

Signal transducer and activator of transcription 3 (acute-phase response factor)

Homo sapiens

Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303.

APRF, HIES, STAT5, APRF, Acute-phase response factor

WB, IHC, IF

21618338

Liquid