STAT4 Antilichaam - N-terminalgebied: HRP (ARP33376-T100-HRP)

Signal transducer and activator of transcription 4

SLEB11

6775

Q14765

NP_003142

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human STAT4

STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

UBC; ADRB2; TRIM28; FHL1; ZNF467; PIAS2; NMI; IL12RB2; IL12RB1; MAP2K6; STAT4; MAPK14; CREBBP; JUN; STAT3; IFNGR1

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

STAT4 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

86kDa

Torpey, N., et al., (2004) J. Biol. Chem. 279 (25), 26789-26796

Wet Ice

748

STAT4

STAT4

Rabbit

Signal transducer and activator of transcription 4

NM_003151

IGGPLHNGLDQLQNCFTLLAESLFQLRRQLEKLEEQSTKMTYEGDPIPMQ