STAU1 Antilichaam

STAU1 Antibody: STAU1 is a member of a family of double-stranded RNA (dsRNA) -binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.

6780

O95793

NP_059347

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

STAU1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

STAU1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

STAU1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

STAU1

Cat. No. 10-301 - Human Brain Tissue Slide

Staufen, RNA binding protein, homolog 1 (Drosophila)

Homo sapiens

Marion RM, Fortes P, Peloso A, et al. A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol. Cell. Biol.1999; 19:2212-9.

De Lucas S, Peredo J, Marion RM, et al. Human Staufen1 protein interacts with influenza virus nucleoproteins and is required for efficient virus multiplication. J. Virol.2010; 84:7603-12.

STAU1 Antibody: STAU, STAU, Double-stranded RNA-binding protein Staufen homolog 1

ELISA, WB, IHC-P, IF

82659087

Liquid