Stearoyl-L-carnitine (chloride) -13C3

Stearoyl-L-carnitine chloride-13C3 is the 13C-labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

12352211

Endogenous Metabolite; GlyT; Isotope-Labeled Compounds

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Metabolism-protein/nucleotide metabolism

Metabolic Disease

O=C(O[C@@H](C[N+]([13CH3])([13CH3])[13CH3])CC(O)=O)CCCCCCCCCCCCCCCCC.[Cl-]

C22 13C3H50ClNO4

467.10

[1]Cristofano A, et, al. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. PLoS One. 2016 May 19;11 (5) :e0155694.|[2]Carland JE, et, al. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br J Pharmacol. 2013 Feb;168 (4) :891-902.|[3]Huang W, et, al. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells. Biochem Pharmacol. 1999 Oct 15;58 (8) :1361-70.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W770914/

Isotope-Labeled Compounds

No Development Reported