STIM-1 Antilichaam

STIM-1 is a component of the Ca sensor/channel. It associates with ORAI-1 and form a essential complex involved in store-operated channels. STIM1 activates Ca (2+) influx via Orai1 channels. Expression of STIM and Orai proteins are found in many cell types and knock-out mice lack viability.

6786

Q13586

EAX02580

Human

A synthetic peptide corresponding to a region near the N-terminus.

Unconjugated

Primary Antibodies

Immunology, Cancer

Affinity Purified

Batch dependent

None

Dry Ice

IgG

ELISA, Western (immuno) blotting, Immunostaining (in testing)

STIM1

Stromal interaction molecule 1

Homo sapiens

Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA., Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation., Biochim Biophys Acta. 2002 Apr 1;1596 (1) :131-137

Dziadek MA, Johnstone LS., Biochemical properties and cellular localisation of STIM proteins., Cell Calcium. 2007 Aug;42 (2) :123-32.

Frischauf I, Schindl R, Derler I, Bergsmann J, Fahrner M, Romanin C., . The STIM/Orai coupling machinery., Channels (Austin) . 2008 Jul-Aug;2 (4) :261-8

Stromal Interaction Molecule 1, GOK, TAM, IMD10, D11S4896E

ELISA, WB, IHC

209572721

Liquid