STIM1 Antilichaam - middelste regio : HRP (ARP45434 P050-HRP)

Stromal interaction molecule 1

GOK, TAM, TAM1, IMD10, STRMK, D11S4896E

6786

Q13586

NP_003147

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the middle region of human STIM1

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs) . It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.

MAPRE1; UBC; SUMO1; NEDD8; S100A16; SEPT11; SEC22B; SF1; CAT; PRKAA2; STIM2; STIM1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

STIM1 is supported by BioGPS gene expression data to be expressed in PANC1

0.5 mg/ml

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

75kDa

Wet Ice

685

STIM1

STIM1

Rabbit

Stromal interaction molecule 1

NM_003156

LDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGS