STIM1 Polyklonale Antilichaam, APC-vervoeging

Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit, TMEM142A/ORAI1.

GOK; TAM; TAM1; IMD10; STRMK; D11S4896E; Stromal interaction molecule 1; STIM1

6786

Q13586

Cytoplasm, Cell membrane

Rat

85-180/685

STIM1

APC

KLH conjugated synthetic peptide derived from human STIM1

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/660nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

May cross react with STIM2

6786

Human, Mouse, Dog, Cow, Pig, Horse, Chicken, Rabbit