Strevertene A

Strevertene A ((-) -Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants[1][2].

235090-14-9

(-) -Strevertene A

12352211

Antibiotic; Endogenous Metabolite; Fungal

Anti-infection; Metabolic Enzyme/Protease

COVID-19-immunoregulation

Infection

O[C@H](C[C@H](O)[C@H]1C)C[C@@H](O)CCC[C@@H](O)C[C@@H](O)[C@@H](C(O)=O)[C@H](O)/C=C/C=C/C=C/C=C/C=C\[C@H](C)[C@@H](C)OC1=O

C31H48O10

580.71

[1]Bonini C, et al. A first convergent synthesis of the polyolic fragment of the antifungal pentaene macrolide strevertene A[J]. Tetrahedron Letters, 2008, 49 (38) : 5455-5457.|[2]Kim JD, et al. Disease control effect of strevertenes produced by Streptomyces psammoticus against tomato fusarium wilt. J Agric Food Chem. 2011 Mar 9;59 (5) :1893-9.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16445/

Natural Products

No Development Reported