STX1A Antilichaam

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.

6804

Q16623

Q16623

Human

This STX1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human STX1A.

Unconjugated

Primary Antibodies

Cancer, Obesity, Neuroscience, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

33 kDa

Rabbit Ig

STX1A

Syntaxin-1A

Homo sapiens

Yoshida, T., et al. Int. J. Mol. Med. 24 (2) :233-246 (2009)

Hamdan, F.F., et al. Ann. Neurol. 65 (6) :748-753 (2009)

Corominas, R., et al. Neurosci. Lett. 455 (2) :105-109 (2009)

Chen, C.S., et al. J. Biol. Chem. 284 (11) :6877-6884 (2009)

Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1

WB, IHC-P, Flow

2501084

Liquid