STXBP5 Antilichaam

Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.

134957

Q5T5C0

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 640-900 of human STXBP5 (NP_640337.3) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 135kDa

IgG

WB: 1:500 - 1:2000

STXBP5

Syntaxin binding protein 5

Homo sapiens

LGL3, LLGL3, Nbla0430syntaxin-binding protein 5, lethal (2) giant larvae protein homolog 3, putative protein product of Nbla0430tomosyn, tomosyn-1

WB

Liquid