Sucralose (GMP Like)

Sucralose (GMP Like) (E955 (GMP Like) ) is the GMP Like class Sucralose that can be used as pharmaceutical excipients. Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents[1][2].

56038-13-2

E955 (GMP Like) ; Trichlorosucrose (GMP Like)

12352005

Endogenous Metabolite

Metabolic Enzyme/Protease

Cancer

ClC[C@]1(O[C@H](CCl)[C@@H](O)[C@@H]1O)O[C@H]([C@@H]([C@@H](O)[C@H]2Cl)O)O[C@@H]2CO

C12H19Cl3O8

397.63

[1]M S, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016 Jan;22 (1) :7-17. |[2]Nabanita Kundu, et al. Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells. Stem Cell Res Ther. 2020 Jun 26;11 (1) :250.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N0614GL/

GMP Small Molecules

No Development Reported