SUMO3 Antilichaam - middengebied: Biotine (ARP58247_P050-Biotine)

SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)

SMT3A, Smt3B, SMT3H1, SUMO-3

6612

P55854

NP_008867

Human

The immunogen is a synthetic peptide directed towards the middle region of human SUMO3

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

PML; USPL1; UBC; HIF1A; ESRRA; EP300; SENP1; USP25; SENP5; SENP2; TP53; SP100; RANGAP1; RGPD8; SUMO3; TRA2B; SDHA; GNB2; GNB1; GART; GAPDH; XRCC6; FLNA; FEN1; FASN; FBL; ENO1; EMD; EIF4A2; EIF4A1; EIF2S1; EEF2; EEF1G; EEF1D; EEF1A1; DNMT1; DYNC1H1; DHX15

Biotin

Polyclonal Antibody

WB, IHC

Affinity Purified

SUMO3 is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

12kDa

Zhang, X.D., (2008) Mol. Cell 29 (6), 729-741

Wet Ice

103

SUMO3

SUMO3

Rabbit

Small ubiquitin-related modifier 3

NM_006936

MRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVPESSLAGHSF