SURF1 Antilichaam

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

6834

Q15526

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 80-275 of human SURF1 (NP_003163.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

SW480

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 33kDa

IgG

SURF1

HL-60

BT-474

SKOV3

Mouse liver

Mouse kidney

SURF1 cytochrome c oxidase assembly factor

Homo sapiens

CMT4K, surfeit locus protein 1, surfeit 1

WB, IHC

Liquid