Survivon Antilichaam [2H5H2]

Baculoviral IAP repeat-containing 5 (survivin) .This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

332

O15392

O15392

Human

Purified full-length recombinant Survivin-His is expressed in E.Coli strain BL21 (DE3) .The antigen is soluble.

2H5H2

Unconjugated

Primary Antibodies

Apoptosis, Growth Factors, Neuroscience, Cancer

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

Survivin monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

BIRC5

Baculoviral IAP repeat containing 5

Homo sapiens

Urology. 2007 Sep;70 (3) :482-6.

World J Gastroenterol. 2007 May 28;13 (20) :2784-90.

Histopathology. 2007 Jun;50 (7) :835-42.

API4, IAP4, Apoptosis inhibitor 4API4, EPR-1

ELISA, WB

380865472