SVS-1 peptide (acetaat)

SVS-1 peptide acetate is an anticancer peptide. SVS-1 peptide acetate can selectively recognize cancer cells through electrostatic interactions, disrupt the cell membrane structure, and lead to cell death. Unlike antimicrobial peptides, the efficacy of SVS-1 peptide acetate occurs before complete neutralization of the membrane charge[1].

12352209

Others

Others

Cancer-programmed cell death

Cancer

99.41

O=C(N(CCC1)[C@@H]1C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CCC2)N2C([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O.[x]

C97H183N27O19.xC2H4O2

2031.66 (free base)

[1]Gaspar D, et al. Anticancer peptide SVS-1: efficacy precedes membrane neutralization. Biochemistry. 2012 Aug 14;51 (32) :6263-5.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10708A/SVS-1-peptide-acetate-SDS-MedChemExpress.pdf

Peptides

No Development Reported