SWAP70 Polyklonale Antilichaam, Biotinevervoeging

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4) -bisphosphate production and cell protrusion.

Switch-associated protein 70; SWAP70; SWAP70; KIAA0640; HSPC321

23075

Q9UH65

Cytoplasm, Cell membrane

Human

131-230/585

SWAP70

Biotin

KLH conjugated synthetic peptide derived from human SWAP70

WB, ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C for 12 months.

23075

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit